Medical Isotope Production at Bruce Power

Long term isotope production opportunities

Bruce Power and Isogen (a joint venture between Kinectrics and Framatome) have partnered to design, manufacture and install a first-of-its-kind Isotope Production System to produce urgently-needed medical isotopes. The System, which is installed at Bruce Power, provides unprecedented capacity and scale for medical isotope production.

To further leverage and utilize the capabilities of the Isotope Production System, Bruce Power L.P. and Isogen Corp issue this Expression of Interest (EOI) in order to solicit information and market opportunities (collectively, “Information”) from entities (the “Proponents”) interested in the production of medical isotopes at the Bruce Power Nuclear Generating Station.

The purpose of this EOI is a first step towards engaging Proponents to secure long-term isotope supply agreements. As such, the EOI aims to gain an understanding of the demand for new, novel, and existing medical isotopes such that Isogen and Bruce Power can plan current and future isotope production capacity and future Isotope Production System functionality and investments.

EOI responses ideally include (as applicable):

  • The medical isotope or isotopes of interest;
  • The required volume of the isotope(s) in Tbq, the desired irradiation time and frequency of harvest;
  • The stable isotope starting material, chemical and physical form, amount (mass), isotopic enrichment level; and
  • Any other required or desired functional, technical or logistical aspect that enable the production and supply of the isotope(s) of interest.

As background, the average expected neutron flux a Proponent can expect for irradiations at the Bruce Power Nuclear Generating Station within the Isotope Production System is approximately 4.5×1014 n/s/cm2.

Note: Isogen and Bruce Power explicitly exclude any and all EOIs related to the production of no-carrier-added Lutetium-177 (nca Lu-177) based on the irradiation of Ytterbium-176 (Yb-176) as well as the production of Cobalt-60.

EOI submission:

Please print, sign and scan the completed EOI including the signed Schedule A. A Word version of Schedule A is provided for your convenience. You are also welcome to include a reasonable amount of supporting documentation when making your submission.

Submissions will be accepted through June 30, 2022 at 5 p.m. EST.